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Takeuchi-Nie Lab
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The lab researches biohybrid technology that combines living organisms and machines.
AboutAbout the lab
Systems where living organisms and machines coexist
Takeuchi-Nie Lab researches "biohybrid systems" that combine living organisms and machines.
Its motto is "Think Hybrid," blending fields such as mechanical engineering, electrical engineering, information science, biology, chemistry, and materials science.
Using MEMS, microfluidic devices, and tissue engineering, the lab works on a new approach to manufacturing that treats DNA, proteins, and cells as "components."
Its research includes muscle-powered robots, odor sensors, cultured meat, and transplantable organs.
Key terms
- Biohybrid
- Combining biological parts, such as cells and proteins, with artificial objects such as machines
- MEMS
- Systems that combine very small sensors and moving parts made with semiconductor fabrication techniques
- Tissue engineering
- Technology for artificially creating body tissue using cells and materials that serve as scaffolds for cells
- Olfactory receptor
- A protein on the surface of a cell that receives and distinguishes odor molecules
NewsLab news
A student received the Excellent Presentation Award at Cheminas53
Announcement of the Open Campus for parents and the graduate school information session for the Graduate School of Information Science and Technology
A paper on a fish-shaped soft robot, which grew out of an undergraduate student's self-initiated project, has been accepted
A student received the President's Award and the Top Prize of the Dean of the Faculty of Engineering Award (Research)
A master's student received the Dean of the Graduate School Award and the Miura Award
ResearchResearch themes
The lab researches biohybrid systems that combine living organisms and machines, organized around four elements: sensors, reactors, actuators, and processors. Building on MEMS and microfluidic device technologies, it works on robots, sensors, cultured meat, artificial cells, implantable devices, and networks of neurons.
*Illustrative imageMuscle-Powered Robots
This research moves robots by electrically stimulating cultured skeletal muscle to make it contract. A pair of muscles placed facing each other, like the muscles of an arm, bends a joint in both directions, and the lab has also succeeded in having the robot lift and carry a ring.
*Illustrative imageSensors That Borrow Biological Smell
The lab researches sensors that use the mechanisms by which cells distinguish odor molecules, such as insect olfactory receptors. It has succeeded in detecting trace amounts of cancer markers mixed into exhaled breath, and in building a robot that moves in response to specific odors.
*Illustrative imageBuilding 3D Tissues from Cells
The goal is to process cells like components and assemble them as if building a machine, producing thick three-dimensional tissues precisely and quickly. Applications are expected in transplant materials for regenerative medicine and in cultured meat.
*Illustrative imageSteak-Like Cultured Meat
The lab grew bovine muscle cells to create cultured meat resembling steak, with muscle fibers aligned in one direction. It was made using only edible materials, and the lab conducted the first tasting experiment of cultured meat at a research institution in Japan.
MembersFaculty
Members of Takeuchi-Nie Lab include faculty, researchers, technical assistants, administrative assistants, doctoral, master's, and undergraduate students, visiting researchers and research students, research trainees, and joint and collaborative researchers.As of 2026
- ProfessorShoji TakeuchiPublications ↗
- LecturerNie MinghaoPublications ↗
- Project LecturerYuna Abe
- Assistant ProfessorByungwook Cho
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Lab on a Chip ( )” National Institute of Standards and Technology / Public domain (cropped)
- Muscle-Powered Robots: “Contractile myotubes in vitro” RigInScience / CC BY 4.0 (cropped)
- Sensors That Borrow Biological Smell: “Bipectinate Antenae of Moth Antheraea sp. Yathumon M A” Yathumon M A / CC BY-SA 4.0 (cropped)
- Building 3D Tissues from Cells: “Co-culture spheroid of HT1376 and RT112 cells” Altyn0707 / CC BY 4.0 (cropped)
- Steak-Like Cultured Meat: “First cultured hamburger unfried” World Economic Forum / CC BY 3.0 (cropped)
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（情報システム工学研究室／Jouhou System Kougaku Laboratory） （岡田研究室） ): “Ars Electronica 2008 Kotaro” Manfred Werner - Tsui / CC BY-SA 3.0 (cropped) - Related lab (生活システム工学研究室
（二瓶研究室） ): “Rollator” DirkvdM / CC BY 3.0 (cropped) - Related lab (Dynamics Control Systems Lab
（深尾研究室） ): “Autonomous compact tractors in a Texas vineyard, Nov 2012” ASIrobots / CC BY-SA 3.0 (cropped) - Related lab (高橋・
白松研究室 （生命知能システム研究室） ): “Axons Al Dente” MikeRoscopy / CC BY 4.0 (cropped)
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