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Viral Pathogenesis and Control Lab
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A lab that uses herpesviruses as a clue to uncover how diseases and cells work.
AboutAbout the lab
Opening up new science through virus research
The Viral Pathogenesis and Control Lab studies how viruses replicate and cause disease, focusing mainly on herpes simplex virus.
Herpes simplex virus causes encephalitis and diseases of the skin and mucous membranes, and no vaccine has been developed yet.
Using viruses as a clue, the lab also uncovers cellular mechanisms that are hard to find in ordinary biological research.
Even if you have no experience in virology or biology, the lab's staff will give you careful guidance.
Key terms
- Herpes simplex virus
- A virus that causes encephalitis and diseases of the skin and mucous membranes. It lies hidden in the body and repeatedly recurs.
- Latent infection
- A state in which a virus remains hidden in the body without causing disease.
- Antiviral drug
- A drug that suppresses the replication of viruses in the body.
NewsLab news
Paper accepted for publication in Journal of Virology
Paper accepted for publication in Journal of Virology
Study demonstrates the body's built-in resistance to viruses (press release)
Graduate student wins third place at the Institute of Medical Science research presentation event
Study elucidates molecular mimicry that governs viral survival strategies (press release)
ResearchResearch themes
Guided by the principle of "opening up new science through virus research," the lab conducts research using herpes simplex virus as a model. In addition to studying how viruses cause disease and how this can be applied in medicine, the lab takes on research that uses viruses as a clue to understand cellular mechanisms, and research that reexamines viruses as factors that maintain homeostasis in the body.
*Illustrative imageHow viruses replicate and cause disease
By analyzing a wide range of infection phenomena together, from entry into cells to gene expression, particle formation, and immune responses, the lab aims to understand the whole picture of how viruses replicate and cause disease. The findings are being linked to the development of new vaccines and antiviral drugs.
*Illustrative imageLearning about cellular mechanisms from viruses
Viruses hijack and exploit cellular mechanisms that are normally dormant. By studying the interactions between viruses and cells in detail, the lab reveals cellular mechanisms that are overlooked in ordinary biological research. One example is the elucidation of the mechanism of nuclear export in cells.
*Illustrative imageReexamining viruses as factors that maintain the body
Herpesviruses coexist with their host for most of its life as latent infections that do not cause disease. Starting from the new idea that latent infection contributes to resistance against bacterial infection and cancer, the lab uncovers the role that viruses play for their host.
MembersFaculty
The members of the lab are composed of faculty members, project researchers, technical staff, academic specialists, doctoral and master's students, research students, visiting professors, visiting researchers, and secretaries.As of 2026
- ProfessorYasushi KawaguchiPublications ↗
- Associate ProfessorYuhei MaruzuruPublications ↗
VoicesStudent voices
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Varicella-zoster Virus ( )” NIAID / CC BY 2.0 (cropped)
- How viruses replicate and cause disease: “Small cell carcinoma infected with herpes simplex virus - Case )” Yale Rosen from USA / CC BY-SA 2.0 (cropped)
- Learning about cellular mechanisms from viruses: “Nuclear membrane” Boumphreyfr / CC BY-SA 3.0 (cropped)
- Reexamining viruses as factors that maintain the body: “Herpes simplex virions, TEM” CDC/ Dr. Fred Murphy / Public domain (cropped)
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