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Kishi Lab
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A lab that seeks to uncover how the brain works through epigenetics, the memory system of the cell.
AboutAbout the lab
Understanding how the brain works through epigenetics
The Molecular Neurobiology Lab studies the roles that epigenetics, the memory system of the cell, plays in the brain.
Chemical modifications attached to DNA and histones work like bookmarks, supporting the mechanism by which only the genes a given cell needs are read.
By combining genome analysis technologies with techniques from genetics and neuroscience, the lab aims to understand changes in the brain caused by aging, stress, and psychiatric disorders.
Key terms
- Epigenetics
- A mechanism that determines which genes are used through chemical modifications and other means, without changing the DNA sequence
- Histone
- A protein that DNA wraps around. Chemical modifications to histones change how easily genes are read
- Genome analysis
- Comprehensively examining the entire set of genetic information in a cell using instruments and computation
NewsLab news
Paper on aging and the hippocampal epigenome published in Aging Cell
Paper on how neurons prepare to acquire their functions published in Development
Results of a collaborative study published in Nature Structural & Molecular Biology
Results of a collaborative study published in Nature Neuroscience
Student wins the Best Oral Presentation Newcomer Award at the Autumn Colloquium of the Young Brain Scientists' Meeting
ResearchResearch themes
The lab works to elucidate the role that epigenetics, the memory system of the cell, plays in the brain, the memory system of the individual. It aims for a world in which changes in brain function caused by aging, stress, and psychiatric disorders can be understood.
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MembersFaculty
The members of the Molecular Neurobiology Lab consist of faculty members, doctoral and master's students, collaborating researchers, cooperating researchers, institute research students, international internship trainees, and academic specialist staff.As of 2026
- Associate ProfessorYusuke KishiPublications ↗
- Assistant ProfessorMerve Bilgic
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Hippocampal Neurons, stained” Ns takes photos / CC BY 4.0 (cropped)
- Understanding the brain through epigenetics: “Nucleosome structure” Richard Wheeler (Zephyris) / CC BY-SA 3.0 (cropped)
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