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International Animal Resource Science Lab (Matsumoto Group)
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The lab studies how disease-causing pathogens interact with the immune systems of animals and humans.
AboutAbout the lab
The battle between pathogens and immunity, seen through animals and humans
The International Animal Resource Science Lab (Matsumoto Group) studies the relationship between pathogenic microorganisms that cause infectious diseases and the immune systems of their host animals.
Using a variety of infection models, the lab investigates how pathogens survive inside the host's body and how the host's immune response suppresses pathogen growth and the onset of disease.
The lab also focuses on mucosal vaccines that do not require injection and on edible vaccines, and is evaluating their efficacy.
Many of the infectious diseases the lab studies are endemic overseas, so the lab also conducts overseas field surveys and international collaborative research.
Key terms
- Host
- An organism that a pathogen enters and lives in. Here, it refers to humans, animals, and birds.
- Edible vaccine
- A vaccine intended to build immunity by being eaten orally rather than injected.
- Liver fluke (Fasciola)
- A flat parasite that lives in the livers of livestock such as cattle and sheep, and of humans.
ResearchResearch themes
The lab is interested in the survival strategies of disease-causing microorganisms inside their hosts, and in the responses of host animals (humans, other animals, and birds). In particular, it uses a variety of infection models to study how the host's immune response suppresses pathogen growth and the onset of disease.
*Illustrative imageEpidemiological Study of Liver Flukes (Fasciola)
The lab investigates where and how the parasitic liver fluke Fasciola is spreading. Because the disease is often endemic overseas, the lab also conducts overseas field surveys and international collaborative research.
*Illustrative imageBiochemical Study of Liver Flukes (Fasciola)
The lab studies the same liver fluke from a biochemical perspective, examining the substances that make up its body and their functions. The lab is interested in how pathogens such as liver flukes survive inside the host's body.
*Illustrative imageLeishmania and Kampo Herbal Medicine
Leishmania is one of the pathogens that cause infectious disease in humans and animals. The lab is searching for Kampo herbal medicines that are effective against this pathogen.
*Illustrative imageAntitumor Therapy Using Viruses
Some strains of Newcastle disease virus, which causes disease in poultry, have the property of destroying tumors. The lab is advancing research on antitumor therapy using this virus.
MembersFaculty
The members of the International Animal Resource Science Lab (Matsumoto Group) consist of faculty members, doctoral, master's, and undergraduate students, graduate research students, and research support staff.
- ProfessorYasunobu MatsumotoPublications ↗
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Osteosarcoma cells stained for actin, microtubules, and nuclei” Howard Vindin / CC BY 4.0 (cropped)
- Epidemiological Study of Liver Flukes (Fasciola): “Fasciola hepatica” Flukeman / CC BY-SA 3.0 (cropped)
- Biochemical Study of Liver Flukes (Fasciola): “Fasciola hepatica 01 Pengo” Peter Halasz / CC BY-SA 3.0 (cropped)
- Leishmania and Kampo Herbal Medicine: “Leishmania (02)” Michael Wunderli / CC BY 2.0 (cropped)
- Antitumor Therapy Using Viruses: “HaCaT Cells Phase Contrast” Accuratelibrarian / CC BY-SA 4.0 (cropped)
- Related lab (International Environmental Economics Lab): “Crops Kansas AST 20010624” NASA / Public domain (cropped)
- Related lab (Global Forest Environment Lab): “8 Aerial view of indigenous forest canopy - N Plettenberg bay” Abu Shawka / CC BY-SA 4.0 (cropped)
- Related lab (International Agricultural Development Lab (Yamamoto Lab)): “Kesennuma Bay - panoramio” Satoh Junpei / CC BY-SA 3.0 (cropped)
- Related lab (International Fisheries Development Lab): “DFC 2234 Colorful fishing boats bob in a calm harbor under a cloudy sky their flags and tarps fluttering in the breeze” PattayaPatrol / CC BY-SA 4.0 (cropped)
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