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Bioregulation Science Lab
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The lab uses chemistry to control plant hormones, aiming to develop better crops.
AboutAbout the lab
Plants can be kept healthy with chemicals, too
The Bioregulation Chemistry Lab studies bioactive substances that are present in only trace amounts in plants, focusing on plant hormones.
Targeting gibberellins and strigolactones, the lab also searches for new, as-yet-unknown plant hormones.
A distinctive feature of the lab is that its research begins with developing methods to control how plant hormones are produced and how they act, using chemical compounds and genes.
Combining chemical and biological perspectives, the lab aims to create crops with better traits and to achieve sustainable agriculture.
Key terms
- Plant hormone
- A substance produced in very small amounts inside a plant that regulates growth, germination, branching, and other processes
- Strigolactone
- A plant hormone that suppresses branching. It also serves as a germination cue for the seeds of root parasitic weeds
- Root parasitic weed
- A weed that parasitizes the roots of crops and takes their nutrients. It causes serious damage in Africa and other regions
- Chemical genetics
- A research method in which compounds are used to alter plant functions, and the genes involved are identified from differences in how the compounds take effect
NewsLab news
A master's student received the Student Excellent Presentation Award at the 51st Annual Meeting of the Pesticide Science Society of Japan
A doctoral student received the Company Recommendation Award at the 60th Annual Meeting of the Japanese Society for Chemical Regulation of Plants
A doctoral student received the Excellent Poster Award at the 39th Symposium of the Pesticide Design Research Group
A master's student received the Hitoshi Matsuo Award at the 60th Anniversary Plant Chemistry Symposium
A master's student received the Excellent Presentation Award at the 2024 Kanto Branch Meeting of the Japan Society for Bioscience, Biotechnology, and Agrochemistry
ResearchResearch themes
The lab investigates the chemistry and physiology of plant hormones and other substances that act in extremely small amounts, as well as the mechanisms by which their signals are transmitted. Using this knowledge, it aims to develop crop production technologies that make use of both chemical compounds and genes.
*Illustrative imageControlling strigolactones with chemistry
Strigolactones are plant hormones that suppress branching and also serve as germination cues for root parasitic weeds. The lab is developing agents that interfere with their biosynthesis, as well as compounds that mimic their action.
*Illustrative imageHow gibberellin signals are transmitted
Gibberellins are plant hormones that promote germination and stem elongation. Through collaborative research, the lab was involved in the discovery of their receptor, and it is now working to elucidate how the signal is transmitted and to search for compounds useful in agriculture.
*Illustrative imageDeveloping regulators and chemical genetics
The lab designs and synthesizes new compounds that control the action of plant hormones such as strigolactones, and applies them to elucidating plant physiological phenomena and discovering useful genes.
*Illustrative imageControlling the action of ethylene
The lab conducts research on preserving crop quality by controlling the action of the plant hormone ethylene, and on elucidating how plants perceive ethylene. It is also developing compounds that control ethylene.
MembersFaculty
The members of the Bioregulation Chemistry Lab consist of faculty, project researchers, administrative assistants, doctoral, master's, and undergraduate students, and collaborating researchers from other universities and research institutions.As of 2026
- ProfessorMasatoshi NakajimaPublications ↗
- Associate ProfessorTakatoshi WakabayashiPublications ↗
- Assistant Professor小山 倫之
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “3-day-old buckwheat sprouts” V.Boldychev / CC BY-SA 4.0 (cropped)
- Controlling strigolactones with chemistry: “Striga hermonthica on maize” Ethan Bass / CC BY-SA 4.0 (cropped)
- How gibberellin signals are transmitted: “Delonix regia germinating seeds” Thebirdbrand / CC BY-SA 4.0 (cropped)
- Developing regulators and chemical genetics: “Rotationsverdampfer” Gmhofmann 12:13, 26. Jun. 2007 (CEST) / Public domain (cropped)
- Controlling the action of ethylene: “Ripening bananas (Unsplash)” Scott Webb scottwebb / CC0 (cropped)
- Related lab (Bioorganic Chemistry Lab): “Malcolmia littorea kz06” Krzysztof Ziarnek, Kenraiz / CC BY-SA 4.0 (cropped)
- Related lab (Organic Chemistry Lab): “Coloured column chromatography ( )” Максим Фомич / CC BY 2.0 (cropped)
- Related lab (Nagata Lab (Team N / Molecular Recognition Chemistry)): “Zweifleckgrille Gryllus bimaculatus 1” Holger Krisp / CC BY 3.0 (cropped)
- Related lab (Molecular Breeding Lab): “20241028-R9HMNF-CB-001 Leafy ground” usfs_Eastern_Region / Public domain (cropped)
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