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Iwano Lab
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A lab that modifies luminescent substrates and enzymes to observe life phenomena through bioluminescence.
AboutAbout the lab
Seeing invisible life phenomena with bioluminescence.
The Iwano Lab studies technologies that capture life phenomena using light, specifically bioluminescence, which is produced by a chemical reaction between a luminescent substrate and an enzyme.
Bioluminescence is widely used in the life sciences, for example in experiments that measure how much a gene is active, and in imaging that examines from outside the body the number and location of labeled cells inside laboratory animals.
Using methods from organic chemistry, protein engineering, and molecular biology, the lab modifies both luminescent substrates and luminescent enzymes to develop new bioluminescence systems.
The lab's website lists three research areas: developing new bioluminescence systems, developing biosensors based on bioluminescence, and developing bioimaging technologies that can be applied up to whole living animals.
Key terms
- Bioluminescence
- Light produced by a chemical reaction between a luminescent substrate and a protein or enzyme. It is used as a tool for capturing life phenomena with light.
- Luminescent substrate
- A small organic molecule that is the source of bioluminescence. It reacts chemically with a luminescent enzyme to emit light.
- Bioimaging
- Technology that makes phenomena occurring inside cells or living organisms visible as images.
ResearchResearch themes
Bioluminescence is light produced by a chemical reaction between a luminescent substrate and a protein or enzyme, and it is widely used as a tool for capturing life phenomena with light. This lab develops new bioluminescence systems by modifying both luminescent substrates and luminescent enzymes, and is applying their properties to bioimaging technologies.
View More ↗MembersFaculty
Members of the Iwano Lab consist of faculty, project researchers, technical assistants, administrative assistants, and part-time student workers.As of 2026
- LecturerSatoshi Iwano
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