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Haeno Lab
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A lab that uses mathematical models to explain how diseases such as cancer progress.
AboutAbout the lab
Explaining disease with equations.
The Haeno Lab represents diseases, with cancer as the leading example, using probabilistic models and differential equations, with the aim of uncovering the principles by which diseases arise.
The lab writes down how cell numbers change over time as mathematical models based on differential equations and stochastic processes, and estimates the model parameters from data obtained through collaborations and the lab's own experiments.
Through computer simulation and mathematical analysis, the lab seeks to understand the whole picture of a disease, aiming to identify drug discovery targets, predict prognosis, and propose optimal treatment strategies.
The lab says it will support people with no experience in mathematical modeling or simulation so that they can learn enough in a short time to use these methods in their research.
Key terms
- Mathematical model
- A description of a phenomenon such as a disease in mathematical equations. In this lab, changes in cell numbers over time are expressed with differential equations and stochastic processes.
- Stochastic process
- A mathematical tool that uses probability to describe changes involving chance as they unfold over time. It is used to study fluctuations in cell numbers.
- Differential equation
- An equation that expresses how fast a quantity changes over time. It is used to describe how cell numbers change over time.
NewsLab news
Paper on geneSCOPE, an analysis tool for detecting gene modules, published in Briefings in Bioinformatics
Review article in Japanese published in the December special issue of Medical Science Digest
Co-authored several entries in the Encyclopedia of Theoretical Biology (Asakura Publishing)
Review article in Japanese, "Cancer Research Using Clinical Data," published in the April issue of Kagaku
Review article in Japanese, "Research Support Using Mathematical Model Analysis in Cancer," published in Seitai no Kagaku
ResearchResearch themes
This lab aims to uncover the principles of diseases, with cancer as the leading example, by representing their pathology with probabilistic models and systems of differential equations. By explaining disease principles in mathematical terms, it aims to identify drug discovery targets, predict prognosis, and propose optimal treatment strategies.
View More ↗MembersFaculty
Members of the Haeno Lab consist of faculty, project researchers, researchers, visiting researchers, international students, doctoral, master's, and undergraduate students, and administrative assistants.As of 2026
- Associate ProfessorHiroshi Haeno
- Assistant ProfessorKouichi Saeki
VoicesStudent voices
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