LAB LOGA page on LabLog, a review site (not the lab's official page)
Matsushima Lab
Machine-translated · View original
The lab studies cytokines and chemokines as a window into inflammation and immunity, aiming to treat intractable inflammatory and immune diseases.
AboutAbout the lab
Decoding inflammation and immunity through a molecular window
The Matsushima Lab studies the mechanisms of inflammatory and immune responses, using cytokines and chemokines (leukocyte chemotactic factors) as a window.
When pathogens or foreign substances enter a tissue, the tissue cells signal the abnormality and, together with immune cells gathered from the blood, eliminate the foreign substances and repair the tissue.
When something goes wrong in this process, the tissue loses its function and disease develops.
Using cutting-edge techniques in gene expression analysis, computational analysis, and immunological analysis, the lab aims to develop treatments for intractable inflammatory and immune diseases that currently have no therapy.
Key terms
- Chemokine
- A molecule also called a leukocyte chemotactic factor. Together with cytokines, the lab uses it as a window for studying inflammatory and immune responses
- Fibrosis
- A change that occurs in organs with chronic inflammation. The lab views it as a state in which homeostasis of the cell-to-cell network has collapsed
- GVHD
- Graft-versus-host disease. It occurs after allogeneic hematopoietic stem cell transplantation for leukemia and other diseases, and is caused by donor T cells
NewsLab news
Professor Koji Matsushima received the IAIS Lifetime Achievement Award
A doctoral student received the Excellent Presentation Award at the 47th Annual Meeting of the Japanese Society of Inflammation and Regeneration
Professor Koji Matsushima received the Prime Minister's Award at the 7th Japan Medical Research and Development Grand Prize
ResearchResearch themes
The lab aims to uncover the mechanisms of inflammatory and immune responses through cytokines and chemokines, and to propose new strategies for the prevention, amelioration, and treatment of inflammatory and immune diseases. Research is carried out in groups organized by project.
Chronic inflammation and organ fibrosis
The lab regards the essence of fibrotic disease as the collapse of homeostasis in the cell-to-cell network. It analyzes fibrotic organs in terms of time and space, at the level of single cells and single-cell transcriptomes, and searches for new treatment strategies.
Drugs to eliminate hepatitis B virus
HBV, the virus that causes hepatitis B, is difficult to eliminate completely after infection. The lab conducts drug discovery research aimed at finding new small-molecule compounds that can eliminate HBV from the body.
New combination immunotherapies for cancer
In the field of cancer immunotherapy, the lab works on developing new combination immunotherapies and clarifying how they work. It also conducts clinical trials to deliver the results of basic research to patients.
Graft-versus-host disease (GVHD)
In allogeneic hematopoietic stem cell transplantation for leukemia and other diseases, GVHD caused by donor T cells is a major factor in poorer prognosis. The lab investigates how the immunodeficiency associated with GVHD arises, using a variety of mouse models.
MembersFaculty
The Matsushima Lab's members include faculty, collaborating faculty from within the university, researchers, academic support staff, engineers and technicians, doctoral and master's students, vocational school students, visiting professors, and visiting researchers.As of 2026
- ProfessorKoji Matsushima
VoicesStudent voices
Ratings and reviews reflect the experiences of individual current or former students, not the lab's official views. Whether a lab has reviews, or how many, says nothing about the lab itself.
Students who take part in an interview may receive a thank-you gift worth ¥1,000, regardless of what they say.
Student ratings (0 students)
--
--
--
--
--
--
Student voices answer questions like these
- What's great about this lab?
- What did you learn after joining?
- What's the vibe, and what is the professor like?
- Who is this lab for?
- Where do graduates go?
Your experience can help younger students choose their lab. Your name won't be shown.
Write a lab reviewAnonymous · Your draft is saved if you stopThe information on this page is compiled by the LabLog team from the lab's public information and interviews. For corrections or removal requests, please contact LabLog, not the lab.
Report an errorAbout LabLog
LabLog is a lab review app for students only. Student members at each university interview students in labs and publish what they say. Student voices can only be read by students who sign up with a university email address. Operated by bestiee Inc.
Learn more about LabLog ↗Search engines and AI may reference the basic lab info and rating summaries on this page and the description of LabLog. Student voices are for student members only. Automated collection by programs (scraping, or input to or training of AI) is prohibited under Article 8 of the Terms of Service. If you need data for research or analysis, please contact us.