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Nakamura Lab
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The lab investigates how neuronal axons extend, using FRET imaging.
AboutAbout the lab
Watching axons grow in living cells.
The Nakamura Lab studies how neurites (axons) grow toward their targets, as part of the process by which neural circuits form in the brain.
The brain is built on a complex but orderly neural network whose units are individual neurons.
For the brain and nervous system to function, a wide variety of neurons must be placed in precise positions and form networks with one another.
The lab investigates axon growth using FRET imaging, a technique that makes it possible to visualize the activity of key signaling molecules in living cells.
Key terms
- Axon
- A neurite extending from a neuron. It grows toward its target.
- Growth cone
- A highly motile structure that uses signal transduction systems to remodel the cytoskeleton and add membrane, thereby growing the axon.
- FRET imaging
- A technique that makes it possible to visualize the activity of key signaling molecules in living cells.
ResearchResearch themes
The lab focuses on how axons grow toward their targets, as part of the formation of the neural circuits that support the function of the brain and nervous system. The university's lab introduction lists the following as example themes: analysis of the signal transduction mechanisms that control axon elongation and guidance; analysis of the regulatory mechanisms of vesicle trafficking in neurons; and the development of a next-generation FRET imaging system.
View More ↗MembersFaculty
- ProfessorTakeshi Nakamura
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