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Endocrinology Lab
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The lab uses fish as a model to explore the molecular mechanisms behind secondary sexual characteristics.
AboutAbout the lab
Uncovering how sex differences arise, using fish
Prof. Ogino's lab uses fish as a model to study, at the level of genes and hormones, how the diverse secondary sexual traits that appear in males arise.
The lab focuses on how secondary sexual traits that differ from species to species relate to the action of androgens and to genome evolution.
Drawing on the results of its basic research, the lab is also working to develop technologies for assessing the effects of endocrine-disrupting chemicals on the development and reproduction of organisms.
Prof. Ogino also teaches in English in the Faculty of Collaborative Regional Innovation, and puts effort into education that cultivates perspectives spanning fields such as ecology and environmental science.
Key terms
- Secondary sexual characteristics
- Differences in body form and behavior that appear between males and females as they mature
- Genome evolution
- Changes over successive generations in the complete set of genetic information of an organism
- Endocrine-disrupting chemicals
- Chemicals that interfere with the action of hormones in organisms. Also known as endocrine disruptors (called "environmental hormones" in Japanese)
ResearchResearch themes
The lab investigates the genetic background and molecular mechanisms of the diverse reproductive strategies of vertebrates and of the secondary sexual traits that have generated species diversity. Using small fish as a model, it analyzes how the expression of traits by hormones relates to genome evolution.
*Illustrative imageMolecular Mechanisms of Secondary Sexual Characteristics
The lab focuses on the expression of the diverse male traits induced by androgens and on how it relates to genome evolution. Using the methods of molecular developmental biology, it examines how hormones act on the developmental processes in which secondary sexual characteristics appear.
*Illustrative imageTechnologies for Assessing the Effects of Endocrine Disruptors
Applying the results of its basic research, the lab is working to build a monitoring system for evaluating the effects of endocrine-disrupting chemicals. It aims to establish a technical foundation for accurately assessing how endocrine disruptors affect the development and reproduction of organisms.
MembersFaculty
- ProfessorYukiko Ogino
VoicesStudent voices
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “20240724 Medaka Miyuki Blue 3 male Foto Manuel Werner DSC0808” Werner, Deutschland / CC BY-SA 4.0 (cropped)
- Molecular Mechanisms of Secondary Sexual Characteristics: “Nihonmedaka” NOZO / CC BY 3.0 (cropped)
- Technologies for Assessing the Effects of Endocrine Disruptors: “A scientist inspects a water sample. ( )” USEPA Environmental-Protection-Agency / Public domain (cropped)
- Related lab (Muscle Cell Biology Lab): “Chick embryo 3d” PaulT (Gunther Tschuch) / CC BY-SA 4.0 (cropped)
- Related lab (Molecular Evolution Lab): “Mikrofoto.de-Hydra 15” Frank Fox / CC BY-SA 3.0 de (cropped)
- Related lab (Molecular Evolution Lab): “Phylogenetic tree for Human PAAT” Yiopanda / CC0 (cropped)
- Related lab (Cognitive Neuroscience Lab): “CT scan of the brain showing recent right basal ganglia bleed” Cerevisae / CC BY-SA 4.0 (cropped)
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