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Mathematical Biology Lab
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A lab that explores the mysteries of life phenomena through mathematical models and data analysis.
AboutAbout the lab
Exploring the mysteries of life through mathematical models and data analysis.
The Mathematical Biology Lab studies the mysteries of life phenomena using mathematical models and data analysis.
Its interests range widely, from mutation, cell-cell interactions, shape, and the adaptive evolution of organisms to changes in human society and the global environment.
Research proceeds from directions such as seasonal adaptation and biological rhythms, the genomic mechanisms that produce individual differences, and the evolution of biological form.
Key terms
- Mathematical model
- A representation of the mechanisms of a life phenomenon in mathematical equations, which are run through computation to study the phenomenon
- Quantitative genetics
- A field of genetics that examines how differences in traits among individuals are linked to differences in DNA sequences
- Ultimate and proximate causation
- Two viewpoints: the reason a trait evolved (ultimate) and the mechanism that produces it (proximate)
NewsLab news
A doctoral student wins the Outstanding Poster Award at the 6th Mathematical Biology Summer School
A paper on isoprene emission and the molecular evolution of terpene synthases in Fagaceae has been published
A paper on the evolutionary origin of the prolonged delay of fertilization in Fagaceae has been published
A paper comparing the molecular phenology of tropical and temperate trees across climates has been published
A mathematical paper that captures flowering time under climate change from the perspective of gene activity has been published
ResearchResearch themes
The lab explores the mysteries of life phenomena by making full use of mathematical models and data analysis. With interests in diverse phenomena, including mutation, cell-cell interactions, shape, the adaptive evolution of organisms, human society, and global environmental change, it takes on unsolved problems.
*Illustrative imageSeasonal Adaptation and Biological Rhythms
Investigates how organisms have adapted to and evolved in their environments in Japan, where temperature and day length change with the seasons, and in the tropics, where seasonal change is small. By integrating seasonal biology and mathematical biology, the lab aims to make predictions for the future.
*Illustrative imageDNA Sequence Differences Underlying Individual Variation
Using natural populations of the model plant Arabidopsis thaliana and its close relative Arabidopsis halleri, the lab investigates, with genomics and quantitative genetics, the DNA sequence differences that create trait differences among individuals, their significance, and gene functions.
*Illustrative imageEvolution of Biological Form
The lab seeks to understand the evolution of biological form quantitatively from both ultimate and proximate perspectives. Theories and techniques for quantifying and modeling form are also applied to agriculture, medicine, materials science, and archaeology.
MembersFaculty
The lab's members consist of faculty, project assistant professors and postdoctoral researchers, JSPS Research Fellows, visiting researchers, doctoral, master's, and undergraduate students, internship students, academic researchers, cooperating faculty, technical staff, secretaries, and professors emeritus.As of 2026
- ProfessorAkiko Satake
- Associate ProfessorEriko Sasaki
- Assistant ProfessorKoji Noshita
- Project Assistant ProfessorValentin Journe
- Project Assistant ProfessorYong-Jin Huang
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Bactritida-ammonoidea evolution morphology” Antonov / Public domain (cropped)
- Seasonal Adaptation and Biological Rhythms: “Circadian clock of mammals” Nitramus / CC BY-SA 3.0 (cropped)
- DNA Sequence Differences Underlying Individual Variation: “TIGR lab Old DNA sequencers” Steve Jurvetson / CC BY 2.0 (cropped)
- Evolution of Biological Form: “Studing of morphology of moths and butterflies from tropical regions. Institute of Systematics and Evolution of Animals Polish Academy of Sciences in Cracov” Karolina Fok / CC BY 4.0 (cropped)
- Related lab (生体高分子機能学研究室): “HeLa-Tubulin-HSP60-Fibrillarin-DNA” GerryShaw / CC BY-SA 4.0 (cropped)
- Related lab (細胞機能学研究室): “Cell cycle showing G0 G1 arrest” Lucia de Diego Mialdea / CC BY-SA 4.0 (cropped)
- Related lab (生態科学研究室): “Carrhotus viduus Jumping spider - Salticidae three-quarter view in Don Det Laos - Focus stacking” Basile Morin / CC BY-SA 4.0 (cropped)
- Related lab (
行動神経科学研究室): “Mouse Brain (NIH BioArt )” Courtesy of NIAID Ryan Kissinger / Public domain (cropped)
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