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Medical Biophysical Chemistry Lab (Cooperating Division)
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A lab that supports regenerative medical engineering by creating materials that control cells.

AboutAbout the lab
Supporting regenerative medical engineering with materials that control cells
To broaden the foundations of regenerative medical engineering, the Medical Biophysical Chemistry Lab approaches research from two sides: the engineering of materials that control cells, and the biophysics of cells.
Using mechanobiology, which studies how cells and tissues respond to their mechanical environment, as a starting point, the lab creates biomaterials that control cell behavior.
The lab also studies, from a physical chemistry perspective, how biopolymers such as DNA and proteins assemble, and it researches the control of cell functions using glycopolymers.
On the lab's website, the lab is introduced under the name "Kidoaki Lab."
Key terms
- Mechanobiology
- A field that studies how cells and tissues respond to the mechanical conditions around them
- Electrospinning
- A method of making fibers using an electric field. In this lab, it is used to make scaffold materials for tissue engineering
- Vimentin
- A protein known as a cytoskeletal molecule. It appears in large amounts at lesion sites in cancerous and fibrotic tissue
ResearchResearch themes
The lab creates materials that control cells while also investigating the physical properties of cells and biomolecules. Through materials development, it aims to broaden the foundations of regenerative medical engineering.
*Illustrative imageMechanobiomaterials for controlling cells
This research creates materials that control cell behavior. Examples given include materials for controlling stem cells, materials for controlling cell migration, materials for inducing tissue regeneration, and materials for diagnosing cancer cells.
*Illustrative imageMaking scaffold materials for tissue engineering
In matrix engineering, the lab uses electrospinning to develop extracellular matrices, scaffolds, and devices for use in tissue engineering.
*Illustrative imageAssembly and mechanics of DNA and proteins
The lab studies from a physical chemistry standpoint how DNA and proteins come together, separate, and self-assemble. This includes research in molecular biomechanics.
*Illustrative imageControlling cells with glycopolymers
The lab aims to control cell functions by using the interactions between synthesized glycopolymers and cells. By targeting vimentin, which appears on the cell surface, it aims to build diagnostics and drug delivery systems for diseases such as cancer and fibrosis.
MembersFaculty
The members of the Medical Biophysical Chemistry Lab are faculty, technical staff, and master's and undergraduate students.As of 2026
- ProfessorSatoru Kidoaki
- Associate ProfessorHirohiko Ise
- Assistant ProfessorThasaneeya Kuboki
VoicesStudent voices
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “SEM Lyophilized Hydrogel Scaffold” Habannn / CC0 (cropped)
- Mechanobiomaterials for controlling cells: “Human Stem Cells ( )” National Center for Advancing Translational Sciences from Bethesda, MD / Public domain (cropped)
- Making scaffold materials for tissue engineering: “3D printed Hydrogel Scaffold” Habannn / CC0 (cropped)
- Assembly and mechanics of DNA and proteins: “DNA Origami Triangular” Matthias A. Fenner / CC BY-SA 4.0 (cropped)
- Controlling cells with glycopolymers: “HaCaT Cells Phase Contrast” Accuratelibrarian / CC BY-SA 4.0 (cropped)
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