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Plasma Applied Science and Engineering Lab
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A lab that applies plasma to medicine, agriculture, and the environment.
AboutAbout the lab
Applying plasma to medicine, biotechnology, agriculture, and the environment
The Plasma Applied Science and Engineering Research Group (Hayashi Lab) researches new technologies that apply plasma to medicine, biotechnology, agriculture, and the environment.
Because plasma is short-lived, it allows safe and harmless applications without the concern of residual agents, unlike chemicals.
The lab develops sterilizers for medical instruments and disinfection devices for agricultural products, and also pursues research on promoting plant growth, killing cancer cells, and activating immune cells.
Key terms
- Plasma
- High-energy particles not normally found in our everyday surroundings. It carries high energy but is short-lived.
- Sterilization
- Killing and eliminating microorganisms such as bacteria. It is used in medicine and the food industry.
- Immune cells
- Cells that eliminate viruses and bacteria and monitor for cancer cells and abnormalities in the body. They include T cells, B cells, and macrophages.
- Spheroid
- A three-dimensional culture model of cancer cells with a structure and properties close to those of actual tumor tissue.
NewsLab news
View More ↗ResearchResearch themes
The lab researches and develops new plasma application technologies that are useful in medicine, biotechnology, agriculture, and the environment. It irradiates immune cells, cancer cells, microorganisms, agricultural products, and seeds with oxygen plasma and other types of plasma, and investigates the effects and mechanisms.
*Illustrative imageActivating immune cells with plasma
The lab proposes a method of activating immune cell function by exposing the cells to oxygen plasma, which can be used safely at atmospheric pressure. Irradiation is known to promote immune cell proliferation, and the current aim is to control cell activation and differentiation.
*Illustrative imageMinimally invasive cancer treatment with plasma
The lab aims for a treatment that selectively inactivates only cancer cells while minimizing effects on normal cells. It irradiates three-dimensional spheroid models of cancer cells with oxygen-helium atmospheric-pressure plasma to examine the characteristics of the inactivation.
*Illustrative imageOxygen plasma sterilizer for medical use
Medical instruments are mainly sterilized with harsh chemicals such as ethylene oxide and peracetic acid. The lab has devised an oxygen plasma sterilization method that is safe and harmless to people and the environment as an alternative, and is researching and developing it toward practical use.
*Illustrative imageSterilizing agricultural products and seeds and promoting growth
Instead of chemicals, the lab is developing methods to sterilize agricultural products and keep them fresh using oxygen plasma and radicals, which have no toxicity or residue. It also studies seed sterilization and the promotion of germination and growth in plasma-treated seeds.
MembersFaculty
The members of the Hayashi Lab consist of faculty, postdoctoral researchers (PDs), and doctoral, master's, and undergraduate students.As of 2026
- ProfessorNobuya Hayashi
- Associate ProfessorYoshihito Yagyu
VoicesStudent voices
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Plasma Jets” Rosser1954 / CC BY-SA 4.0 (cropped)
- Activating immune cells with plasma: “Immune Cells (NIH BioArt 253)” Courtesy of NIAID Ryan Kissinger / Public domain (cropped)
- Minimally invasive cancer treatment with plasma: “Plasma Pencil” Entropi5 / CC BY-SA 3.0 (cropped)
- Oxygen plasma sterilizer for medical use: “Systec H-Series Autoclaves” Foto Studio Wiegand / CC BY-SA 4.0 (cropped)
- Sterilizing agricultural products and seeds and promoting growth: “Разнообразие семян” Alexander Klepnev / CC BY 4.0 (cropped)
- Related lab (Functional Materials Physics Lab): “Bloated rechargeable batteries” Tobias ToMar Maier / CC BY-SA 3.0 (cropped)
- Related lab (Mass Transfer and Reaction Engineering Lab): “Hydrogen (Element - 1)” James St. John / CC BY 2.0 (cropped)
- Related lab (Fusion Plasma Properties and Control Engineering Lab): “Soldering practice object for tokamak construction, in park of Tsukuba Expo Center” Syced / CC0 (cropped)
- Related lab (Ionization Reaction Engineering Lab): “Minimal Fab exhibit at Tsukuba Science Square 5” Syced / CC0 (cropped)
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