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Applied Analytical Chemistry Lab
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An analytical chemistry lab that examines cells and bacteria on tiny chips.
AboutAbout the lab
Examining cells and bacteria on a tiny chip
The Kaji Lab studies new bioanalytical technologies that measure biological substances and cells, using micro- and nanospaces made with microfabrication techniques from the semiconductor field.
Toward the early detection of cancer and bacterial infections, the lab aims to develop analytical methods that place less burden on patients from blood sampling or biopsy.
The lab's ultimate goal is to create Life-on-a-Chip, which artificially reproduces biological phenomena on a chip.
This website belongs to Professor Kaji's group, the “Kaji Research Group.”
Key terms
- Microfluidic device
- A small chip in which liquid flows through tiny channels made by microfabrication, used to examine cells and other samples
- Extracellular vesicle
- A particle released by cells, about 50 nm to several micrometers in diameter. It contains nucleic acids and proteins
- Life-on-a-Chip
- A concept that extends analytical Lab-on-a-Chip further, aiming to artificially reproduce biological phenomena on a chip
NewsLab news
A paper by a master's student and a graduate accepted by Analyst
A paper from joint research with Southeast University accepted by Lab on a Chip
A paper by a graduate accepted by ACS Omega
A paper by a graduate accepted by Analytical and Bioanalytical Chemistry
A paper by a graduate accepted by Optics Express
ResearchResearch themes
To detect cancer and infections early, the lab aims to create minimally invasive or noninvasive analytical methods that place less burden on patients from blood sampling or biopsy. It uses micro- and nanospaces made with semiconductor microfabrication technology as places to measure cells and biological substances, and its future goal is to realize Life-on-a-Chip, which reproduces biological phenomena on a chip.
*Illustrative imageAn analysis method that diagnoses cells by touch
Genetic sequences and the like are mostly examined by analyses that destroy cells, so they cannot be used for quality assurance of cells in regenerative medicine. The lab is developing a single-cell analysis method that neither stains nor destroys cells, using microfluidic devices that can “diagnose by touch.”
*Illustrative imageFabrication and analysis of artificial cells and extracellular vesicles
Among extracellular vesicles, exosomes in particular are expected to serve as new disease biomarkers that can be collected in a minimally invasive way. The lab is developing devices that examine, one by one, each particle's physical properties and information about its contents, aiming to recover useful vesicles and apply them in medicine.
*Illustrative imageA chip for studying the gut microbiota
How the environment in which gut bacteria coexist forms is not well understood. The lab aims to develop a method that uses microfabrication to create a gut-like environment and observe when, where, and how bacteria settle in the body.
*Illustrative imageAnalytical technology using laser light
The lab studies analytical technologies that combine new tools not previously used in analytical chemistry with laser light sources it has developed itself. The “dispersion-compensated high-finesse cavity” is a mechanism first proposed by the lab.
MembersFaculty
The members of the Kaji Lab consist of faculty, master's and undergraduate students, and research students.As of 2026
- ProfessorNoritada Kaji
- Assistant ProfessorYiwei Liang
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “GEMBE; lab-on-a-chip ( )” National Institute of Standards and Technology / Public domain (cropped)
- An analysis method that diagnoses cells by touch: “Atomic force microscope by Zureks” Zureks / CC BY-SA 3.0 (cropped)
- Fabrication and analysis of artificial cells and extracellular vesicles: “Phosphatidylcholine liposomes stained with acridine orange” ArkhipovSergey / CC BY-SA 4.0 (cropped)
- A chip for studying the gut microbiota: “Lab on a Chip ( )” National Institute of Standards and Technology / Public domain (cropped)
- Analytical technology using laser light: “Portable RAMAN Laser Spectrometer ( )” IAEA Imagebank / CC BY 2.0 (cropped)
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