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Quantum Information Systems Lab
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The lab works on quantum computers and on enhancing the sensitivity of magnetic resonance.
AboutAbout the lab
Quantum computers and enhanced sensitivity for magnetic resonance
The Quantum Information Systems Lab (Negoro Group) studies quantum information and magnetic resonance (NMR, ESR, MRI).
In quantum information, the lab develops and operates microwave devices that control superconducting qubits, as well as a cloud service for superconducting quantum computers.
In magnetic resonance, the lab studies techniques that use light to align the orientation of nuclear spins in order to increase the sensitivity of NMR and MRI.
The Negoro Group is based at the Center for Quantum Information and Quantum Biology (QIQB) at Osaka University, and its research page states that, with a Visiting Associate Professor appointment at the Graduate School of Engineering Science, the group collaborates closely with the Fujii Lab.
Key terms
- Qubit
- The smallest unit that carries information in a quantum computer
- Nuclear spin
- A magnetic property of atomic nuclei. Their orientations are normally random, which is the reason for the low sensitivity of NMR and MRI
- Triplet DNP
- A dynamic nuclear polarization method that uses light to align electron spins and transfers that alignment to nuclear spins, aligning them at room temperature
- Quantum machine learning
- Machine learning that uses quantum computers
NewsLab news
QuEL, Inc. (where Negoro serves as CSO) wins the Minister of Education, Culture, Sports, Science and Technology Award at the University-Originated Venture Awards 2024
An ultra-high-performance computing platform using superconducting quantum computers wins the Prime Minister's Award at the 53rd Japan Industrial Technology Grand Prize
Cloud service launched for Japan's third domestically built superconducting quantum computer, installed at Osaka University
ResearchResearch themes
The lab develops quantum computers (superconducting and trapped-ion) and works on enhancing the sensitivity of magnetic resonance (NMR/MRI) with quantum technology. Across the two fields of quantum information and magnetic resonance (NMR, ESR, MRI), its research ranges from developing control devices to applications in medical diagnosis.
*Illustrative imageMicrowave devices for controlling qubits
Superconducting qubits and electron-spin qubits are controlled with microwave pulses from a few GHz to 20 GHz. The lab develops low-cost, compact, and highly flexible microwave devices, and runs experiments in which they control actual qubits.
*Illustrative imageCloud operation of a superconducting quantum computer
The lab runs a cloud service, using software, on hardware that combines the control devices it developed with superconducting chips provided by RIKEN. It also researches new pulse control and calibration methods and carries out demonstrations of large-scale quantum information processing.
*Illustrative imageQuantum machine learning with NMR
Within machine learning on quantum computers, the lab implements algorithms that can run even on near-term quantum devices (such as quantum circuit learning and quantum kernel learning) on NMR quantum computers, which use nuclear spins in molecules as qubits.
*Illustrative imageAligning nuclear spins with light
Nuclear spins are normally oriented randomly, which is the reason for the low sensitivity of NMR and MRI. Triplet DNP uses light to align electron spins and transfers that alignment to nuclear spins, and it can do so at room temperature. The lab studies how to achieve higher polarization and how to apply the method to a wider range of molecules.
MembersFaculty
The Negoro Group's members consist of faculty, project researchers, project technical specialists, project academic policy researchers, and affiliated staff (faculty, project researchers, project administrative staff, and administrative assistants).As of 2025
- ProfessorMakoto Negoro
- Associate ProfessorKazuhisa Ogawa
- Project Associate ProfessorHidehisa Shiomi
- Project Associate ProfessorYAP YUNG SZEN
- Associate ProfessorAlto Osada
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Alice and Bob Cryostat” Nilhope / CC BY-SA 4.0 (cropped)
- Microwave devices for controlling qubits: “Superconducting Metamaterial Waveguide Chip” OJB Quantum / CC BY 4.0 (cropped)
- Cloud operation of a superconducting quantum computer: “Dilution Fridge with Quantum Processors Enclosed 008 8K” OJB Quantum / CC BY 4.0 (cropped)
- Quantum machine learning with NMR: “NMR spectrometer” Daniel Alexandre / CC BY-SA 3.0 (cropped)
- Aligning nuclear spins with light: “MRI-Philips” Jan Ainali / CC BY 3.0 (cropped)
- Related lab (Advanced Thin-Film Functional Properties Lab): “Organic CMOS logic circuit” Yasunori Takeda et al. / CC BY 4.0 (cropped)
- Related lab (Information Systems Synthesis Lab): “Embedded World 2014 Atmel Acqua A5” Ordercrazy / CC0 (cropped)
- Related lab (Intelligent Data Science Lab): “August 2010, Monitors displaying real-time data transmitted from the CTD ( )” USEPA Environmental-Protection-Agency / Public domain (cropped)
- Related lab (Media Integration Environment Lab): “VR Mersin Project Pano-X Bot V3” Panoramicweb / CC BY-SA 4.0 (cropped)
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